SetupLauncher.exe is a .NET application and requires a minimum of .NET 2.0 SP2 to run. If .NET-related Critical Updates have recently been installed from Windows Update and the computer has not been rebooted, Setup Launcher may not be able to run properly.
When accessing SetupLauncher.exe from a remote computer, no error messages will appear to inform you of the .NET compatibility issue. The application will just close. If you experience this, verify that .NET 2.0 SP2 or higher (.NET 3.5 SP1 includes all .NET 2.0 components) is installed. If it is, check for pending reboots, then try again.